Biomarker Acquisition and Quality Control for Multi-Site Studies: The Autism Biomarkers Consortium for Clinical Trials.

The objective of the Autism Biomarkers Consortium for Clinical Trials (ABC-CT) is to evaluate a set of lab-based behavioral video tracking (VT), electroencephalography (EEG), and eye tracking (ET) measures for use in clinical trials with children with autism spectrum disorder (ASD). Within the larger organizational structure of the ABC-CT, the Data Acquisition and Analytic Core (DAAC) oversees the standardization of VT, EEG, and ET data acquisition, data processing, and data analysis.

This includes designing and documenting data acquisition and analytic protocols and manuals; facilitating site training in acquisition; data acquisition quality control (QC); derivation and validation of dependent variables (DVs); and analytic deliverables including preparation of data for submission to the National Database for Autism Research (NDAR).

.

Mouse Serum Amyloid A (SAA) ELISA Kit

DLR-SAA-Mu-48T 48T
EUR 489
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Mouse Serum Amyloid A (SAA) ELISA Kit

DLR-SAA-Mu-96T 96T
EUR 635
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Serum Amyloid A (SAA) ELISA Kit

DLR-SAA-Rb-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Serum Amyloid A (SAA) ELISA Kit

DLR-SAA-Rb-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Serum Amyloid A (SAA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-b-48Tests 48 Tests
EUR 580

Bovine Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-b-96Tests 96 Tests
EUR 807

Human Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-Hu-48Tests 48 Tests
EUR 500

Human Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-Hu-96Tests 96 Tests
EUR 692

Mouse Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-Mu-48Tests 48 Tests
EUR 511

Mouse Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-Mu-96Tests 96 Tests
EUR 709

Rabbit Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-Rb-48Tests 48 Tests
EUR 534

Rabbit Serum Amyloid A (SAA) ELISA Kit

RDR-SAA-Rb-96Tests 96 Tests
EUR 742

Bovine Serum Amyloid A (SAA) ELISA Kit

RD-SAA-b-48Tests 48 Tests
EUR 555

Bovine Serum Amyloid A (SAA) ELISA Kit

RD-SAA-b-96Tests 96 Tests
EUR 771

Human Serum Amyloid A (SAA) ELISA Kit

RD-SAA-Hu-48Tests 48 Tests
EUR 478

Human Serum Amyloid A (SAA) ELISA Kit

RD-SAA-Hu-96Tests 96 Tests
EUR 662

Mouse Serum Amyloid A (SAA) ELISA Kit

RD-SAA-Mu-48Tests 48 Tests
EUR 489

Mouse Serum Amyloid A (SAA) ELISA Kit

RD-SAA-Mu-96Tests 96 Tests
EUR 677

Rabbit Serum Amyloid A (SAA) ELISA Kit

RD-SAA-Rb-48Tests 48 Tests
EUR 511

Rabbit Serum Amyloid A (SAA) ELISA Kit

RD-SAA-Rb-96Tests 96 Tests
EUR 709

TruStrip RDT Human Serum Amyloid A (SAA) Rapid Test cards, 10 tests/pack

SAA-RDT-10 1 pack
EUR 171

TruStrip RDT Human Serum Amyloid A (SAA) Rapid Test cards, 25 tests/pack

SAA-RDT-25 1 pack
EUR 293

SAA-PEG-SAA

abx085047-10kDa1g 10 kDa; 1 g
EUR 453

SAA-PEG-SAA

abx085047-1kDa1g 1 kDa; 1 g
EUR 453

SAA-PEG-SAA

abx085047-20kDa1g 20 kDa; 1 g
EUR 453

SAA-PEG-SAA

abx085047-2kDa1g 2 kDa; 1 g
EUR 453

Individual Reaction Mix 9

G065-9 200 reactions
EUR 167

7095B 9 PASTEUR PIPET

7095B-9 200/pk
EUR 70
Description: Disposable Pipets; Pasteur Pipets

7095D 9 PASTEUR PIPET BOROSILICATE

7095D-9 200/pk
EUR 78
Description: Disposable Pipets; Pasteur Pipets

SAA-PEG-SAA,10K

33-HO015015-10K
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,1K

33-HO015015-1K
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,20K

33-HO015015-20K
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,2K

33-HO015015-2K
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,3.4K

33-HO015015-3.4K
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA-PEG-SAA,5K

33-HO015015-5K
  • EUR 259.00
  • EUR 677.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

SAA

E64C01201 20ug
EUR 382

Human Brain Tissue Preparation Buffer 9: Normal Nerve Microglia

9-80021 1 x 100 ml Ask for price

Human Cancer Tissue Preparation Buffer 9: Kidney Tumor Cells

9-80032 1 x 100 ml Ask for price

Mouse Brain Tissue Preparation Buffer 9: Normal Nerve Microglia

9-80132 1 x 100 ml Ask for price

Rat Brain Tissue Preparation Buffer 9: Normal Neuron Cells

9-80227 1 x 100 ml Ask for price

SAA antibody

10R-10351 100 ug
EUR 435
Description: Mouse monoclonal SAA antibody

SAA antibody

10-7959 500 ug
EUR 349
Description: Mouse monoclonal SAA antibody

SAA antibody

10-7960 500 ug
EUR 349
Description: Mouse monoclonal SAA antibody

SAA antibody

20-1715 1 ml
EUR 138
Description: Goat polyclonal SAA antibody

SAA Protein

abx060299-100ug 100 ug
EUR 829

mPEG-SAA

abx085023-10kDa1g 10 kDa; 1 g
EUR 370

mPEG-SAA

abx085023-1kDa1g 1 kDa; 1 g
EUR 356

mPEG-SAA

abx085023-20kDa1g 20 kDa; 1 g
EUR 370

mPEG-SAA

abx085023-2kDa1g 2 kDa; 1 g
EUR 356

mPEG-SAA

abx085023-5kDa1g 5 kDa; 1 g
EUR 356

Bovine(SAA)

QY-E60061 96T
EUR 426

Human Angiotensin 1-9 (Ang1-9) ELISA Kit

DLR-Ang1-9-Hu-48T 48T
EUR 501
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Angiotensin 1-9 (Ang1-9) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Angiotensin 1-9 (Ang1-9) ELISA Kit

DLR-Ang1-9-Hu-96T 96T
EUR 651
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Angiotensin 1-9 (Ang1-9) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Angiotensin 1-9 (Ang1-9) ELISA Kit

RD-Ang1-9-Hu-48Tests 48 Tests
EUR 503

Human Angiotensin 1-9 (Ang1-9) ELISA Kit

RD-Ang1-9-Hu-96Tests 96 Tests
EUR 697

Human Angiotensin 1-9 (Ang1-9) ELISA Kit

RDR-Ang1-9-Hu-48Tests 48 Tests
EUR 525

Human Angiotensin 1-9 (Ang1-9) ELISA Kit

RDR-Ang1-9-Hu-96Tests 96 Tests
EUR 729

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

DLR-CA19-9-Hu-48T 48T
EUR 441
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

DLR-CA19-9-Hu-96T 96T
EUR 570
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 19-9 (CA19-9) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RD-CA19-9-Hu-48Tests 48 Tests
EUR 436

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RD-CA19-9-Hu-96Tests 96 Tests
EUR 601

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RDR-CA19-9-Hu-48Tests 48 Tests
EUR 455

Human Carbohydrate Antigen 19-9 (CA19-9) ELISA Kit

RDR-CA19-9-Hu-96Tests 96 Tests
EUR 629

Apo SAA antibody

20R-1792 100 ug
EUR 673
Description: Rabbit polyclonal Apo SAA antibody

mPEG-SAA,10K

33-MF001015-10K
  • EUR 211.00
  • EUR 531.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,1K

33-MF001015-1K
  • EUR 198.00
  • EUR 494.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,20K

33-MF001015-20K
  • EUR 211.00
  • EUR 531.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,2K

33-MF001015-2K
  • EUR 198.00
  • EUR 494.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,30K

33-MF001015-30K
  • EUR 211.00
  • EUR 531.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,4K

33-MF001015-4K
  • EUR 198.00
  • EUR 494.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

mPEG-SAA,5K

33-MF001015-5K
  • EUR 198.00
  • EUR 494.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

Recombinant Human SAA

P0209 100ug
EUR 522.36
Description: Recombinant Human protein for SAA

SAA ELISA KIT|Human

EF000259 96 Tests
EUR 689

Apo-SAA, human recombinant

4324-10
EUR 137

Apo-SAA, human recombinant

4324-1000
EUR 920

Apo-SAA, human recombinant

4324-50
EUR 256

Apo-SAA, human recombinant

4324-500
EUR 756

Cat SAA ELISA Kit

E-20SAA 1 x 96 well plate
EUR 461

Chicken SAA ELISA Kit

E-30SAA 1 x 96 well plate
EUR 492

Dog SAA ELISA Kit

E-40SAA 1 x 96 well plate
EUR 461

Horse SAA ELISA Kit

E-70SAA 1 x 96 well plate
EUR 517

Human SAA ELISA Kit

E-80SAA 1 x 96 well plate
EUR 461

Mouse SAA ELISA Kit

E-90SAA 1 x 96 well plate
EUR 395

Sheep SAA ELISA Kit

ESS0235 96Tests
EUR 521

Rabbit SAA ELISA Kit

ERTS0235 96Tests
EUR 521

Human SAA ELISA Kit

DEIA450 96T
EUR 1060
Description: ThisHuman SAA ELISA Kit is to be used for the in vitro quantitative determinationof human serum amyloid A (SAA) concentrations in serum, plasma, cell culture supernatant, and other biological fluids.

Monkey SAA ELISA Kit

EMKS0235 96Tests
EUR 521

Mouse SAA ELISA Kit

EMS0235 96Tests
EUR 521

Porcine SAA ELISA Kit

EPS0235 96Tests
EUR 521

Rat SAA ELISA Kit

ERS0235 96Tests
EUR 521

Canine SAA ELISA Kit

ECS0235 96Tests
EUR 521

Bovine SAA ELISA Kit

EBS0235 96Tests
EUR 521

Chicken SAA ELISA Kit

ECKS0235 96Tests
EUR 521

Goat SAA ELISA Kit

EGTS0235 96Tests
EUR 521

Human SAA ELISA Kit

EHS0235 96Tests
EUR 521

Anserini SAA ELISA Kit

EAS0235 96Tests
EUR 521

4-Arm PEG-SAA

abx085101-10kDa1g 10 kDa; 1 g
EUR 384

4-Arm PEG-SAA

abx085101-10kDa5g 10 kDa; 5 g
EUR 634

4-Arm PEG-SAA

abx085101-20kDa5g 20 kDa; 5 g
EUR 634

4-Arm PEG-SAA

abx085101-2kDa1g 2 kDa; 1 g
EUR 356

8-Arm PEG-SAA

abx085112-10kDa1g 10 kDa; 1 g
EUR 328

8-Arm PEG-SAA

abx085112-10kDa5g 10 kDa; 5 g
EUR 620

8-Arm PEG-SAA

abx085112-20kDa5g 20 kDa; 5 g
EUR 620

8-Arm PEG-SAA

abx085112-40kDa1g 40 kDa; 1 g
EUR 356

4-ArmPEG-SAA,10K

33-A44015-10K
  • EUR 174.00
  • EUR 420.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

4-ArmPEG-SAA,20K

33-A44015-20K
  • EUR 174.00
  • EUR 420.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

4-ArmPEG-SAA,2K

33-A44015-2K
  • EUR 198.00
  • EUR 494.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

8-ArmPEG-SAA,10K

33-A88015-10K
  • EUR 149.00
  • EUR 346.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

8-ArmPEG-SAA,20K

33-A88015-20K
  • EUR 149.00
  • EUR 346.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

8-ArmPEG-SAA,40K

33-A88015-40K
  • EUR 174.00
  • EUR 420.00
  • 1g
  • 5g
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.

CEA (Cancer antigen) ELISA test

9 96T/Box Ask for price
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

Recombinant Serum Amyloid A (SAA)

4-RPA885Bo01
  • EUR 440.48
  • EUR 221.00
  • EUR 1376.80
  • EUR 525.60
  • EUR 951.20
  • EUR 358.00
  • EUR 3292.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Bovine Serum Amyloid A expressed in: E.coli

Recombinant Serum Amyloid A (SAA)

4-RPA885Hu01
  • EUR 368.80
  • EUR 202.00
  • EUR 1108.00
  • EUR 436.00
  • EUR 772.00
  • EUR 310.00
  • EUR 2620.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Serum Amyloid A expressed in: E.coli

Recombinant Serum Amyloid A (SAA)

4-RPA885Mu01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Serum Amyloid A expressed in: E.coli

Recombinant Serum Amyloid A (SAA)

4-RPA885Rb01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rabbit Serum Amyloid A expressed in: E.coli

Recombinant Human Apo-SAA Protein

PROTP0DJI8-2 50ug
EUR 317
Description: Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 μg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence. Recombinant Apo-SAA is a consensus SAA molecule corresponding to human apo-SAA1α except for the presence of an N-terminal methionine and substitution of asparagine for aspartic acid at position 60 and arginine for histidine at position 71(the latter two substituted residues are present in apo-SAA2β).

Guinea Pig SAA ELISA Kit

EGS0235 96Tests
EUR 521

Serum Amyloid A (SAA) Antibody

20-abx132400
  • EUR 314.00
  • EUR 787.00
  • EUR 411.00
  • EUR 154.00
  • EUR 258.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Serum Amyloid A (SAA) Antibody

20-abx101239
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Serum Amyloid A (SAA) Antibody

20-abx101240
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

To oversee consistent application of scientific standards and methodological rigor for data acquisition, processing, and analytics, we developed standard operating procedures that reflect the logistical needs of multi-site research, and the need for well-articulated, transparent processes that can be implemented in future clinical trials.

This report details the methodology of the ABC-CT related to acquisition and QC in our Feasibility and Main Study phases. Based on our acquisition metrics from a preplanned interim analysis, we report high levels of acquisition success utilizing VT, EEG, and ET experiments in a relatively large sample of children with ASD and typical development (TD), with data acquired across multiple sites and use of a manualized training and acquisition protocol.