Month: May 2021

Synergistic Killing and Re-Sensitization of Pseudomonas aeruginosa to Antibiotics by Phage-Antibiotic Combination Treatment

Synergistic Killing and Re-Sensitization of Pseudomonas aeruginosa to Antibiotics by Phage-Antibiotic Combination Treatment

Multidrug-resistant (MDR) Pseudomonas aeruginosa infections pose a severe well being menace. Bacteriophage-antibiotic mixture remedy is a promising candidate for combating these infections. A 5-phage P. aeruginosa cocktail, PAM2H, was examined together with antibiotics (ceftazidime, ciprofloxacin, gentamicin, meropenem) to decide if PAM2H enhances antibiotic exercise. Combination remedy in vitro resulted in a big improve in susceptibility of MDR strains to …

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Improving the Inhibitory Effect of Phages against Pseudomonas aeruginosa Isolated from a Burn Patient Using a Combination of Phages and Antibiotics

Improving the Inhibitory Effect of Phages against Pseudomonas aeruginosa Isolated from a Burn Patient Using a Combination of Phages and Antibiotics

Antibiotic resistance causes around 700,000 deaths a year worldwide. Without immediate action, we are fast approaching a post-antibiotic era in which common infections can result in death. Pseudomonas aeruginosa is the leading cause of nosocomial infection and is also one of the three bacterial pathogens in the WHO list of priority bacteria for developing new antibiotics against. …

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